Changes

Mammals are able to synthesize up to 18 carbon saturated fatty acids (i.e. stearic acid) from [[Carbohydrates Overview - Nutrition|glucose]] and [[Amino Acids Overview - Nutrition|glucogenic amino acids]]. They are also able to insert a double bond in the 9 position using the Δ9 desaturase enzyme to form the monounsaturated fatty acid, oleic acid (18:1n9), but are unable to desaturate below that. Oleic acid and medium-chain triglycerides (MCT; fatty acids 8-12 carbons long), are not essential dietary nutrients. Dogs and cats like other mammals have a '''dietary requirement for certain polyunsaturated fatty acids''' within the [[Omega-3 Fatty Acids - Nutrition|omega 3]]  and [[Omega-6 Fatty Acids - Nutrition|omega 6]]  families. Plants have Δ9 desaturase activity as well as varying amounts of Δ12 desaturase and Δ15 desaturase activity. Species differences in plants enable them to concentrate variable amounts of the long-chain and very long chain polyunsaturated fatty acids of the omega 3 and 6 families in their seeds or fleshy fruit.

Mammals are able to synthesize up to 18 carbon saturated fatty acids (i.e. stearic acid) from [[Carbohydrates Overview - Nutrition|glucose]] and [[Amino Acids Overview - Nutrition|glucogenic amino acids]]. They are also able to insert a double bond in the 9 position using the Δ9 desaturase enzyme to form the monounsaturated fatty acid, oleic acid (18:1n9), but are unable to desaturate below that. Oleic acid and medium-chain triglycerides (MCT; fatty acids 8-12 carbons long), are not essential dietary nutrients. Dogs and cats like other mammals have a '''dietary requirement for certain polyunsaturated fatty acids''' within the [[Omega-3 Fatty Acids - Nutrition|omega 3]]  and [[Omega-6 Fatty Acids - Nutrition|omega 6]]  families. Plants have Δ9 desaturase activity as well as varying amounts of Δ12 desaturase and Δ15 desaturase activity. Species differences in plants enable them to concentrate variable amounts of the long-chain and very long chain polyunsaturated fatty acids of the omega 3 and 6 families in their seeds or fleshy fruit.

[[Omega-6 Fatty Acids - Nutrition|Omega-6]] and [[Omega-3 Fatty Acids - Nutrition|omega 3]] fatty acids of equal carbon lengths '''compete for the same enzymes structures''' throughout metabolism and mammals are unable to convert between the two families. Because of this competitive inhibition and inability to alter family grouping, the total FA content of the diet as well as the ratio of specific fatty acids (e.g. AA:EPA) must be considered when evaluating fatty acid requirements and recommendations.  

[[Omega-6 Fatty Acids - Nutrition|Omega-6]] and [[Omega-3 Fatty Acids - Nutrition|omega 3]] fatty acids of equal carbon lengths '''compete for the same enzymes structures''' throughout metabolism and mammals are unable to convert between the two families. Because of this competitive inhibition and inability to alter family grouping, the total FA content of the diet as well as the ratio of specific fatty acids (e.g. AA:EPA) must be considered when evaluating fatty acid requirements and recommendations.