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==What is Vitamin B1 (Thiamin)?==

==What is Vitamin B1 (Thiamin)?==

Vitamin B₁, also called '''thiamin''', is an '''essential water-soluble vitamin''' used in glucose and amino acid metabolism and energy production. Thiamin is readily absorbed across the intestinal mucosa via [[Active Transport - Physiology|active carrier-mediated transport]] as well as via [[Diffusion - Physiology|passive diffusion]]. Once in the enterocyte, thiamin can either be converted to thiamin pyrophosphate (TPP) for immediate use in the cell, or transported as thiamin into the portal circulation to the [[Liver - Anatomy & Physiology|liver]]. Once in the liver it is rapidly distributed throughout the body. Thiamin can be found as a free vitamin within the [[plasma]], but is largely found as part of TPP within [[Erythrocyte|erythrocytes]] and [[leukocytes]]. '''Thiamin is not stored in the body and is freely filtered by the Nephron Microscopic Anatomy#Proximal Tubule|renal tubules]]'''.

Vitamin B₁, also called '''thiamin''', is an '''essential water-soluble vitamin''' used in glucose and amino acid metabolism and energy production. Thiamin is readily absorbed across the intestinal mucosa via [[Active Transport - Physiology|active carrier-mediated transport]] as well as via [[Diffusion - Physiology|passive diffusion]]. Once in the enterocyte, thiamin can either be converted to thiamin pyrophosphate (TPP) for immediate use in the cell, or transported as thiamin into the portal circulation to the [[Liver - Anatomy & Physiology|liver]]. Once in the liver it is rapidly distributed throughout the body. Thiamin can be found as a free vitamin within the [[plasma]], but is largely found as part of TPP within [[Erythrocyte|erythrocytes]] and [[leukocytes]]. '''Thiamin is not stored in the body and is freely filtered by the [[Nephron Microscopic Anatomy#Proximal Tubule|renal tubules]]'''.

==Why is it Important?==

==Why is it Important?==