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* Changes characteristic of the cycle of the bitch include growth and proliferation of the mammary gland with each cycle even if the bitch does not conceive.
 
* Changes characteristic of the cycle of the bitch include growth and proliferation of the mammary gland with each cycle even if the bitch does not conceive.
* Frequent proliferation and subsequent involution predisposes the bitch to mammary tumours.
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* Frequent proliferation and subsequent [[Lactation_-_Involution_-_Anatomy_%26_Physiology|involution]] predisposes the bitch to mammary tumours.
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