Diagnosis of cobalamin deficiency is based on presence of low fasted serum cobalamin level. If the patient is not fasted prior to testing, falsely increased cobalamin concentrations may be noted. Megaloblastic anaemia and neutropenia with hypersegmentation may be seen on haematology profile.
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Diagnosis of cobalamin deficiency is based on presence of low fasted serum cobalamin level. If the patient is not fasted prior to testing, falsely increased cobalamin concentrations may be noted. [[Nutrition Glossary#Megaloblastic Anaemia|Megaloblastic anaemia]] and [[neutropenia]] with hypersegmentation may be seen on haematology profile.
Diagnosis is also made on clinical signs consistent with deficiency and evaluation of diet.
Diagnosis is also made on clinical signs consistent with deficiency and evaluation of diet.