Changes

[[File:Fat digestibility.jpg|right|300px|thumb|© Diffomédia/Masure]]

[[File:Fat digestibility.jpg|right|300px|thumb|© Diffomédia/Masure]]

'''[[Fat Overview - Nutrition|Fat]] and [[Fatty Acids - Nutrition|fatty acid (FA)]] digestion begins in the [[Monogastric Stomach - Anatomy & Physiology|stomach]] of both dogs and cats''' and involves coordination of the [[Pancreas - Anatomy & Physiology|pancreas]], [[Gall Bladder - Anatomy & Physiology|gall bladder]], and [[Small Intestine - Anatomy & Physiology|small intestine]] for optimal absorption.<ref name="NRC">National Research Council (NRC). (2006) '''Fat and Fatty Acids.''''' In Nutrient Requirements for Dogs and Cats. '' Washington, DC: National Academies Press p.86-87.</ref> In the stomach, gastric lipase cleaves triglycerides into free fatty acids (FFA). Once in the [[Duodenum - Anatomy & Physiology|duodenal lumen]], the FFAs stimulate secretion of cholecystokinin (CCK), which in turn stimulates gall bladder and pancreatic contraction. Pancreatic lipase and colipase further cleave FFAs, cholesterol and fat-soluble [[Vitamins - Nutrition|vitamins]] from the ingested fat, which are emulsified with [[Bile salts|bile salts]] from the gall bladder to form a mixed micelle. The mixed micelles are then absorbed into the jejunal enterocytes by passive [[Diffusion - Physiology|diffusion]] (the primary mechanism of uptake) or carrier-mediated uptake, with specific binding proteins for cholesterol and long- and medium-chained FA chains. Resorption of bile salts by the [[Jejunum - Anatomy & Physiology|jejunum]] is low, with the majority of reabsorption occurring in the [[Ileum - Anatomy & Physiology|ileum]]. Once in the enterocyte the FAs, cholesterol, and other phospholipids present are packaged into a lipoprotein rich compound called a chylomicron which is secreted into the intestinal lymphatic systems (lacteals). A smaller portion of dietary fat also passes directly into the portal circulation.

'''[[Fat Overview - Nutrition|Fat]] and [[Fatty Acids - Nutrition|fatty acid (FA)]] digestion begins in the [[Monogastric Stomach - Anatomy & Physiology|stomach]] of both dogs and cats''' and involves coordination of the [[Pancreas - Anatomy & Physiology|pancreas]], [[Gall Bladder - Anatomy & Physiology|gall bladder]], and [[Small Intestine - Anatomy & Physiology|small intestine]] for optimal absorption.<ref name="NRC">National Research Council (NRC). (2006) '''Fat and Fatty Acids.''''' In Nutrient Requirements for Dogs and Cats. '' Washington, DC: National Academies Press p.86-87.</ref> In the stomach, gastric lipase cleaves triglycerides into free fatty acids (FFA). Once in the [[Duodenum - Anatomy & Physiology|duodenal lumen]], the FFAs stimulate secretion of cholecystokinin (CCK), which in turn stimulates gall bladder and pancreatic contraction. Pancreatic lipase and colipase further cleave FFAs, cholesterol and fat-soluble [[Vitamins - Nutrition|vitamins]] from the ingested fat, which are emulsified with [[Bile acids|bile salts]] from the gall bladder to form a mixed micelle. The mixed micelles are then absorbed into the jejunal enterocytes by passive [[Diffusion - Physiology|diffusion]] (the primary mechanism of uptake) or carrier-mediated uptake, with specific binding proteins for cholesterol and long- and medium-chained FA chains. Resorption of bile salts by the [[Jejunum - Anatomy & Physiology|jejunum]] is low, with the majority of reabsorption occurring in the [[Ileum - Anatomy & Physiology|ileum]]. Once in the enterocyte the FAs, cholesterol, and other phospholipids present are packaged into a lipoprotein rich compound called a chylomicron which is secreted into the intestinal lymphatic systems (lacteals). A smaller portion of dietary fat also passes directly into the portal circulation.