Protein requirements increase during growth and reproduction to meet the additional demands for tissue deposition and milk production. Cats and dogs have a relatively high protein requirement which is thought to be due to diet induced evolutionary adaptions<ref>Morris, J.G. Idiosyncratic nutrient requirements of cats appear to be diet-induced evolutionary adaptations. Nutr Res Rev 2002;15; 153-168.</ref>; both species have evolved on high protein meat based diets and this may explain why they have a relatively high metabolic set point for protein catabolism and higher urinary nitrogen loss compared with herbivores, or other omnivores<ref>Hendricks WH, et al. Urinary excretion of endogenous nitrogen metabolites in adult domestic cats using a protein-free diet and the regression technique. J Nutr 1997;127:623-629.</ref>. Cats have a particularly high protein requirement, because unlike the dog and most other animals, they are unable to down regulate urea cycle enzymes in response to low protein diets<ref>Biourge V, et al. Nitrogen balance, plasma free amino acid concentrations and urinary orotic acid excretion during long-term fasting in cats. J Nutr 1994;124:1094-1103.</ref>. | Protein requirements increase during growth and reproduction to meet the additional demands for tissue deposition and milk production. Cats and dogs have a relatively high protein requirement which is thought to be due to diet induced evolutionary adaptions<ref>Morris, J.G. Idiosyncratic nutrient requirements of cats appear to be diet-induced evolutionary adaptations. Nutr Res Rev 2002;15; 153-168.</ref>; both species have evolved on high protein meat based diets and this may explain why they have a relatively high metabolic set point for protein catabolism and higher urinary nitrogen loss compared with herbivores, or other omnivores<ref>Hendricks WH, et al. Urinary excretion of endogenous nitrogen metabolites in adult domestic cats using a protein-free diet and the regression technique. J Nutr 1997;127:623-629.</ref>. Cats have a particularly high protein requirement, because unlike the dog and most other animals, they are unable to down regulate urea cycle enzymes in response to low protein diets<ref>Biourge V, et al. Nitrogen balance, plasma free amino acid concentrations and urinary orotic acid excretion during long-term fasting in cats. J Nutr 1994;124:1094-1103.</ref>. |