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→Recognised Syndromes Related to Chloride Deficiency
====Recognised Syndromes Related to Chloride Deficiency====
====Recognised Syndromes Related to Chloride Deficiency====
Signs of chloride deficiency were observed in puppies fed a milk substitute diet containing 0.021% chloride on a dry matter (DM) basis. After two weeks puppies developed low plasma chloride and potassium and a metabolic alkalosis. General weakness, ataxia and stunted growth were noted. In comparison, puppies fed a diet with a chloride content of about 0.3% DM showed normal growth and no abnormalities<ref>Felder, C, Robillard, J, Roy III, S, Jose, P (1987). “Severe chloride deficiency in the neonate: The canine puppy as an animal model”. Pediat. Res. 21:497-501.</ref>.
Signs of chloride deficiency were observed in puppies fed a milk substitute diet containing 0.021% chloride on a dry matter (DM) basis. After two weeks puppies developed low plasma chloride and [[Potassium - Nutrition|potassium]] and a metabolic alkalosis. General weakness, ataxia and stunted growth were noted. In comparison, puppies fed a diet with a chloride content of about 0.3% DM showed normal growth and no abnormalities<ref>Felder, C, Robillard, J, Roy III, S, Jose, P (1987). “Severe chloride deficiency in the neonate: The canine puppy as an animal model”. Pediat. Res. 21:497-501.</ref>.
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