− | As with dogs, the reports of adverse effects of iron are limited to studies of the administration of acute doses. Hoppe et al<ref>Hoppe, J, Marcelli, G, Tainter,M (1955a). “An experimental study of the toxicity of ferrous gluconate”. Am. J. Med. Sci. 230:491-498.</ref> found that acute oral doses of ferrous sulphate or gluconate equivalent to 16 to 128 mg iron per kg BW resulted in [[Vomiting|vomiting]] within one hour of administration. The same researchers found that the median lethal dose of ferrous sulphate heptahydrate in cats was greater than 500 mg iron per kg BW<ref>Hoppe, J, Marcelli, G, Tainter,M (1955b). “Progress of medical science therapeutics: A review of the toxicity of iron compounds”. Am. J. Med. Sci. 230:558-571.</ref>. In relation to the degree of toxicity, these results are broadly in line with those from the dog studies. | + | As with dogs, the reports of adverse effects of iron are limited to studies of the administration of acute doses. Hoppe ''et al''<ref>Hoppe, J, Marcelli, G, Tainter,M (1955a). “An experimental study of the toxicity of ferrous gluconate”. Am. J. Med. Sci. 230:491-498.</ref> found that acute oral doses of ferrous sulphate or gluconate equivalent to 16 to 128 mg iron per kg BW resulted in [[Vomiting|vomiting]] within one hour of administration. The same researchers found that the median lethal dose of ferrous sulphate heptahydrate in cats was greater than 500 mg iron per kg BW<ref>Hoppe, J, Marcelli, G, Tainter,M (1955b). “Progress of medical science therapeutics: A review of the toxicity of iron compounds”. Am. J. Med. Sci. 230:558-571.</ref>. In relation to the degree of toxicity, these results are broadly in line with those from the dog studies. |