− | There are no published reports of vitamin E toxicity in dogs, though in cats high levels of dietary vitamin E can result in prolonged bleeding times<ref>Strieker MJ, et al. Vitamin K deficiency in cats fed commercial fish-based diets. J Small Anim Prac 1996;37:322-326.</ref>. High dosage of vitamin E supplementation in people has also been associated with increased risk of mortality<ref>Bjelakovic G, et al. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention systematic review and meta-analysis. JAMA 2007;297:842-857.</ref>, though this effect has not been studied in dogs and cats. | + | There are no published reports of vitamin E toxicity in dogs, though in cats high levels of dietary vitamin E can result in prolonged [[Coagulation Tests|bleeding times]]<ref>Strieker MJ, et al. Vitamin K deficiency in cats fed commercial fish-based diets. J Small Anim Prac 1996;37:322-326.</ref>. High dosage of vitamin E supplementation in people has also been associated with increased risk of mortality<ref>Bjelakovic G, et al. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention systematic review and meta-analysis. JAMA 2007;297:842-857.</ref>, though this effect has not been studied in dogs and cats. |