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==Histology==
 
==Histology==
 
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*At the anus, the columnar intestinal epithelium is replaced by the stratified squamous epithelium of the skin.
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*As the muscosa changes from columnar to cutaneous, three zones are created:
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**'''Columnar'''
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***Has many longitudinal folds.
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***Divided from the rectum by the ''anorectal line''.
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****This is a line where the mucosa is stratified squamous epithelium containing lots of lymphoid tissue.
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**'''Intermediate'''
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***Divided from the cutaneous zone by the ''anocutaneous line''.
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**'''Cutaneous'''
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***Skin.
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***Stratified squamous epithelium.
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***Surrounds the anus.
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***Excretory ducts of the anal sacs open into this region.
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****Anal sacs are large, coiled apocrine tubules.
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****Anal sacs have many glands in their walls.
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****These glands are tubuloalveolar and produce a fatty secretion.
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****Anal sacs are clinically important as they are commonly diseased in dogs - frequently, they become enlarged due to accumulated secretion.
    
==Species Differences==
 
==Species Differences==
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