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− | '''''Mammogenesis'''''
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| + | == Mammogenesis == |
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| * Initial duct growth is stimulated by '''oestrogen''', '''growth hormone''' and '''glucocorticoids'''. | | * Initial duct growth is stimulated by '''oestrogen''', '''growth hormone''' and '''glucocorticoids'''. |
| * '''Prolactin''' and '''progesterone''' are important for lobular alveolar growth. | | * '''Prolactin''' and '''progesterone''' are important for lobular alveolar growth. |
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| + | ---- |
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| + | == Lactogenesis and Galactopoesis == |
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− | '''''Lactogenesis and Galactopoesis'''''
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| * Regulated by a '''lactogenic complex''' consisting of mainly prolactin and growth hormone, but also thyroid hormones, corticosteroids and insulin. | | * Regulated by a '''lactogenic complex''' consisting of mainly prolactin and growth hormone, but also thyroid hormones, corticosteroids and insulin. |
| * '''Prolactin''' acts on mammary secretory epithelial cells to stimulate synthesis of milk proteins. It is released during suckling and in response to the rise in oestrogen and glucocorticoids in parturition. | | * '''Prolactin''' acts on mammary secretory epithelial cells to stimulate synthesis of milk proteins. It is released during suckling and in response to the rise in oestrogen and glucocorticoids in parturition. |
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| * Depends on the frequency of suckling stimulus to cause release of the lactogenic complex. | | * Depends on the frequency of suckling stimulus to cause release of the lactogenic complex. |
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| + | ---- |
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| + | == Milk Ejection Reflex == |
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− | '''''Milk Ejection Reflex'''''
| |
| * '''[[Endocrine_System_-_Pituitary_Gland_-_Anatomy_%26_Physiology#Oxytocin|Oxytocin]]''' is synthesised by magnocellar neurones of the '''Paraventricular nucleus (PVN)''' and '''Supraoptic nucleus (SON)''' of the '''[[Endocrine_System_-_Hypothalamus_-_Anatomy_%26_Physiology#Hypothalamus|Hypothalamus]] '''. | | * '''[[Endocrine_System_-_Pituitary_Gland_-_Anatomy_%26_Physiology#Oxytocin|Oxytocin]]''' is synthesised by magnocellar neurones of the '''Paraventricular nucleus (PVN)''' and '''Supraoptic nucleus (SON)''' of the '''[[Endocrine_System_-_Hypothalamus_-_Anatomy_%26_Physiology#Hypothalamus|Hypothalamus]] '''. |
| * Oxytocin is secreted from the '''[[Endocrine_System_-_Pituitary_Gland_-_Anatomy_%26_Physiology#Posterior_Pituitary_Gland|Posterior Pituitary Gland]]'''. | | * Oxytocin is secreted from the '''[[Endocrine_System_-_Pituitary_Gland_-_Anatomy_%26_Physiology#Posterior_Pituitary_Gland|Posterior Pituitary Gland]]'''. |