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Adrenogenital Syndrome (view source)
Revision as of 14:25, 23 December 2010
, 14:25, 23 December 2010no edit summary
== Aetiology ==
== Aetiology ==
* Genotype is XX as should be female
* Genotype is XX as should be female
* Ovaries develop normally
* Ovaries develop normally
* Foetal [[Endocrine_System_-_Adrenal_Glands_-_Anatomy_%26_Physiology|Adrenal Gland]] is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''21 hydroxylase mutation'''.
* Foetal [[Adrenal_Glands_- Anatomy & Physiology|Adrenal Gland]] is hyperactive and secretes large quantities of Adrenal Androgens, due to a '''21 hydroxylase mutation'''.
* Mullarian Ducts persist due to the absence of testes, hence absence of Sertoli cell MIH secretion. This allows formation of '''female internal genitalia'''.
* Mullarian Ducts persist due to the absence of testes, hence absence of Sertoli cell MIH secretion. This allows formation of '''female internal genitalia'''.
== Morphology ==
* Appears male with a '''micropenis and scrotum'''
* Both male and female internal genitalia
[[Category:Reproductive Disorders]]
[[Category:Reproductive Diseases - Dog]][[Category:Reproductive Diseases - Cat]]