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→Development of Bone and Cartilage
****Perichondrium differentiates to osteoblasts
****Perichondrium differentiates to osteoblasts
***Capillary invasion to central core, forming trabecular bone
***Capillary invasion to central core, forming trabecular bone
*Bone Growth and Remodeling
**Short bones: endochondral ossification continues in diaphysis until only cartilage rim remains
**Long bones: secondary center of ossification develops in epiphyses
***'''Epiphyseal Growth Plate''': transverse disc of cartilate between the two ossification centers, allows longitudinal growth to continue to maturity, then closes
**'''Primary''' bone has not yet been '''remodelled'''
***Contains less mineral and more randomly arranged collagen fibers, trabecular organization
**Remodelling occurs by '''Haversian canals'''
***Osteoclasts dig out canal, followed by blood vessel invasion
***Concentric lamellae laid down
***Phased resorption happens concurrently
==Types of Bone==
==Types of Bone==