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Follicles - Anatomy & Physiology (view source)
Revision as of 18:18, 16 July 2008
, 18:18, 16 July 2008→Follicular Development
==Follicular Development==
==Follicular Development==
'''Primordial Follicle'''
*Smallest and most immature follicle
*Smallest and most immature follicle
*Oocyte surrounded by a Single layer of squamous cells
*Oocyte surrounded by a Single layer of squamous cells
'''Primary Follicle'''
*Oocyte surrounded by a single layer of follicular cuboidal cells.
*Oocyte surrounded by a single layer of follicular cuboidal cells.
'''Secondary Follicles'''
*The oocyte had developed a thick translucent glycoprotein layer called the Zona Pellucida.
*The oocyte had developed a thick translucent glycoprotein layer called the Zona Pellucida.
*Oocyte surrounded by two or more layers of follicular cuboidal cells. These cells differenciate into the inner Granulosa cells and outer Theca cells.
*Oocyte surrounded by two or more layers of follicular cuboidal cells. These cells differenciate into the inner Granulosa cells and outer Theca cells.
'''Tertiary/Antral Follicles'''
*The innermost cells of the Granulosa layer become firmly attached to the Zona Pellucida and are known as the Corona Radiata. The outermost Granulosa cells become attached to the basement membrane surrounding them and become known as the Theca Folliculi.
*The innermost cells of the Granulosa layer become firmly attached to the Zona Pellucida and are known as the Corona Radiata. The outermost Granulosa cells become attached to the basement membrane surrounding them and become known as the Theca Folliculi.
*Granulosa cells secrete fluid which accumulates within the follicle forming an Antrum.
*Granulosa cells secrete fluid which accumulates within the follicle forming an Antrum.