[[Image:Colon fox lymphatic nodule.jpg|thumb|right|150px|Lymphatic Nodule - Copywright RVC 2008]]
[[Image:Colon fox lymphatic nodule.jpg|thumb|right|150px|Lymphatic Nodule - Copywright RVC 2008]]
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*Lymphatic nodules are present in the mucosa.
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*Lymphatic nodules are present in the mucosa of the large intestine.
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*Lymph nodes of the large intestine drain into one of two centres, the '''cranial mesenteric centre''' or the '''caudal mesenteric centre'''.
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**The '''cranial mesenteric centre''' includes lymph nodes of the [[Small Intestine - Anatomy & Physiology|small intestine]] and the following lymph nodes of the large intestine:
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**'''Caecal''' - drains the caecum.
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**'''Colic''' - drains the ascending and transverse colon.
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***The efferent vessels of these lymph nodes converge to form the cranial mesenteric trunk which drains into the chyle cistern.
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**The '''caudal mesenteric centre''' includes the lymph nodes of the descending colon, which are situated in the mesocolon.
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***The efferent vessels of these lymph nodes converge to form the caudal mesenteric trunk which unites with the cranial mesenteric trunk to open into the chyle cistern.