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Spleen - Anatomy & Physiology (view source)
Revision as of 15:59, 17 July 2008
, 15:59, 17 July 2008→Species Differences
<p>White pulp is organised in relation to the splenic arterioles and consists of discrete lymphoid tissue surrounding a central arteriole. There is a sheath of T-cells directly around the arteriole, the periarteriolar lymphoid sheath (PALS), which is surrounded by a marginal sinus, and then a zone of B-cells and macrophages (the marginal zone). B cell follicles are associated with the marginal zone and expand and develop germinal centres after antigen activation. The marginal sinuses are linked to the red pulp sinuses. </p><p>White pulp stains basophilc in a H&E stain</p>
<p>White pulp is organised in relation to the splenic arterioles and consists of discrete lymphoid tissue surrounding a central arteriole. There is a sheath of T-cells directly around the arteriole, the periarteriolar lymphoid sheath (PALS), which is surrounded by a marginal sinus, and then a zone of B-cells and macrophages (the marginal zone). B cell follicles are associated with the marginal zone and expand and develop germinal centres after antigen activation. The marginal sinuses are linked to the red pulp sinuses. </p><p>White pulp stains basophilc in a H&E stain</p>
====Species Differences====
====Species Differences====
{|align="right"
|[[Image:LH_Spleen_Equine_photo.jpg|110px|<p>'''Equine spleen'''</p>]]
|[[Image:LH_Spleen_Bovine_photo.jpg|156px|<p>'''Bovine Spleen'''</p>]]
|-
!Equine
!Bovine
|-
|colspan="2"|<center><sup>©Nottingham Uni 2008 </sup></center>
|}
<p>The capsule and trabeculae are much more muscular in carnivores and horses than ruminants</p>
<p>The capsule and trabeculae are much more muscular in carnivores and horses than ruminants</p>
*Carnivores
*Carnivores