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mLine 28:
Line 28: − +
→Johne's disease
This study:
This study:
BALB/c mice are susceptible to M.paratuberculosis infection
BALB/c mice are susceptible to M.paratuberculosis infection
γδ T cells KO mice produced fewer granulomas than controls and lower numbers of organisms in the spleen.
γδ T cells KO mice produced fewer granulomas than controls and lower numbers of organisms in the [[Spleen - Anatomy & Physiology|spleen]].
Therefore γδ T cells may be involved in granuloma formation
Therefore γδ T cells may be involved in granuloma formation
γδ T cells in bovines produce TH1 type of cytokines – IFNγ, TNFα and IL-2. May recruit macrophages via production of MCP-1.
γδ T cells in bovines produce TH1 type of cytokines – IFNγ, TNFα and IL-2. May recruit macrophages via production of MCP-1.