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→Structure and Function of Cartilage
*Structure:
*Structure:
**'''Chondrocytes''': reside within '''lacunae''' within ECM synthesizing '''matrix'''
**'''Chondrocytes''': reside within '''lacunae''' within ECM synthesizing '''matrix'''
**Type II Collagen (except fibrocartilage), proteoglycans with associated glycosaminoglycans and hyaluronic acid
**Type II Collagen (except fibrocartilage)
**Proteoglycans with associated glycosaminoglycans
***Continually turned over
***The most vulnerable component of cartilage
***Decresed proteoglycan -> loss of lubrication -> collagen disruption -> frays, clefts, fibrillation, ulcers, exposure of bone, [[Musculoskeletal terminology|eburnation, +/- osteophytes and joint mice]]
**Hyaluronic acid
**75% Water
**75% Water
**Avascular: nutrients/waste move via diffusion
**Avascular: nutrients/waste move via diffusion
**'''Hyaline Cartilage'''
**'''Hyaline Cartilage'''
***Most abundant in the body: glassy, translucent sheen
***Most abundant in the body: glassy, translucent sheen
***Normally blue-white, smooth with moist surface, Turns yellow and becomes thinner in old age
***Found in nose, trachea, bronchi, ventral ends of ribs and sternal attachmont
***Found in nose, trachea, bronchi, ventral ends of ribs and sternal attachmont
***Surrounded by perichondrium
***Surrounded by perichondrium