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== Introduction ==
 
== Introduction ==
 
Alkaline phophatase (ALP) is widely distributed in tissue and intepretation of a serum elevation is difficult due to age and species differences and lack of information. It is part of a standard biochemistry profile in mammals but its significance in reptiles is unknown and its interpretation unknown. It may be a constituent of some laboratories' reptilian profiles.
 
Alkaline phophatase (ALP) is widely distributed in tissue and intepretation of a serum elevation is difficult due to age and species differences and lack of information. It is part of a standard biochemistry profile in mammals but its significance in reptiles is unknown and its interpretation unknown. It may be a constituent of some laboratories' reptilian profiles.
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==== Complementary tests ====
 
==== Complementary tests ====
 
ALP activity is usually determined in conjunction with other tests of hepatocellular damage or hepatic function, specifically [[Aspartate aminotransferase|AST]], GGT, GLDH and bile acids. Intestinal ALP is useful where intestinal pathology is suspected or the ALP activity is increased without other biochemical evidence of hepatic disease. Interpretation should take into consideration the age related reference ranges for serum and intestinal ALP, particularly high results in immature horses and foals.
 
ALP activity is usually determined in conjunction with other tests of hepatocellular damage or hepatic function, specifically [[Aspartate aminotransferase|AST]], GGT, GLDH and bile acids. Intestinal ALP is useful where intestinal pathology is suspected or the ALP activity is increased without other biochemical evidence of hepatic disease. Interpretation should take into consideration the age related reference ranges for serum and intestinal ALP, particularly high results in immature horses and foals.
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== IAP (Intestinal alkaline phosphatase) ==
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In horses, the intestinal isoenzyme of ALP may be released as a consequence of intestinal pathology. Increased IAP activity is associated with conditions such as intestinal parasitism, scouring and localised intestinal hypoxia following surgery. This test is of limited utility due to its short half life.
    
== Authors and References ==
 
== Authors and References ==
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[[Category:Lizard_and_Snake_Glossary|A]]
 
[[Category:Lizard_and_Snake_Glossary|A]]
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[[Category:Clinical Chemistry|AB]]

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