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Leucocyte pattern recognition (view source)
Revision as of 17:07, 15 March 2022
, 17:07, 15 March 2022no edit summary
== Neutrophilia ==
== Neutrophilia ==
Initially an acute inflammatory stimulus, mediated through cytokines, causes release of the storage pool of mature neutrophils from the bone marrow. If the stimulus persists band neutrophils, metamyelocytes and occasionally myelocytes and promyelocytes are released from the bone marrow granulocyte pool. This is evident in the peripheral circulation a left shift.
Initially an acute inflammatory stimulus, mediated through cytokines, causes release of the storage pool of mature neutrophils from the bone marrow. If the stimulus persists band neutrophils, metamyelocytes and occasionally myelocytes and promyelocytes are released from the bone marrow granulocyte pool. This is evident in the peripheral circulation a left shift.
[[File:NWLLabfacts 30.jpg|thumb|Left Shift NationWide Laboratories]]
[[File:NWLLabfacts 30.jpg|thumb|'''Left Shift''' ©NationWide Laboratories 2017 ]]
A left shift of >1.0 x109/l band cells is diagnostic for inflammatory disease. Milder left shifts (0.3-1.0 x109/l bands) may occur with haemorrhage, chronic or granulomatous inflammation.
A left shift of >1.0 x109/l band cells is diagnostic for inflammatory disease. Milder left shifts (0.3-1.0 x109/l bands) may occur with haemorrhage, chronic or granulomatous inflammation.