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*Commensals on skin and mucous membranes of animals and man
*Commensals on skin and mucous membranes of animals and man
*Enodgenous or exogenous infections
*Enodgenous or exogenous infections
*Opportunistic pyogenic infections associa
*Opportunistic pyogenic infections associated with trauma, immusuppression, other infections
*Coagulase-positive 'S. aureus'' and ''S. intermedius'' as well as ''S. hyicus'' are important pathogens of animals
*Coagulase-positive 'S. aureus'' and ''S. intermedius'' as well as ''S. hyicus'' are important pathogens of animals
*Fairly stable in environment
*Fairly stable in environment
*Strains selective for particular species
*Strains selective for particular species
*Cause mastitis, tick pyaemia, exudative epidermitis, botryomycosis and pyoderma
===
===Bovine mastitis===
*''S. aureus'' is a common cause of mastitisin cattle worldwide
*Most infections subclinical
*Systemic infection can occur with peracute and gangrenous forms
*In gangrenous mastitis, the quarter may become necrotic and slough off; alpha toxin causes necrosis of smooth muscle in blood vessel walls, reducing blood flow to the affected quarter, and causes release of lysomal enzymes from leukocytes
===Tick pyaemia===
*Infection of lambs with ''S. aureus'' in hill-grazing areas of the UK
*Lambs carry ''S. aureus'' on their skin and nasal mucosa; infection via skin trauma including tick bites
*''Ixodes ricinus'' tick acts as a vector for ''Ehrlichia phagocytophila'', which causes immunosuppression in lambs, predisposing to staphylococcal infection
*Acute septicaemia and death or localised abscess formation in many organs
*Arthritis, posterior paresis and ill-thrift
*Microscopic identification of bacteria in pus and isolation of ''S. aureus''
*Prophylactic antibiotics e.g. tetracyclines initiated at 1 week of age may prevent infection
*Tick control important
===Exudative epidermitis (greasy pig disease===
*Worldwide disease of pigs under 3 months of age caused by ''S. hyicus''
*Highly contagious
*Excessive sebacious secretion and exudation on surface of skin
*Pigs are anorexic, febrile, depressed and have a greasy, non-pruritic dermatitis
*Acute death in piglets under 3 weeks
*20-100% morbidity; up to 90% mortality
*Organism enters skin via abrasions e.g. bite wounds
*Carried in vaginal mucosa and skin of sows
*Predisposed by lack of milk, weaning and other infections
*Isolation from skin lesions
*Early systemic antibiotics amd topical antiseptics/antibiotics useful
*Disinfection after outbreak
*Wash sows before farrowing
===Botryomycosis===
*Chronic, suppurative granulomatous condition
*''S. aureus''
*Occurs following castration of horses due to infection of stump of spermatic cors
*Occurs in mammary tissues of sows
*Mass of fibrous tissue containing pus and sinus tracts
===Infections in dogs and cats===
*''S. intermedius'' causes pyoderma, otitis externa, mastitis, endometritis, cystitis, osteomyelitis, wound infections