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*Coagulase-negative strains vary in ability to cause haemolysis
 
*Coagulase-negative strains vary in ability to cause haemolysis
 
*Slide test to detect bound coagulase (clumping factor) on surface of bacteria; bacteria clump within 1-2 minutes
 
*Slide test to detect bound coagulase (clumping factor) on surface of bacteria; bacteria clump within 1-2 minutes
*Tube test detects free coagulase, secreted by bactera; positive result indicated by clot formation in tube following 24-hour incubation
+
*Tube test detects free coagulase, secreted by bactera; positive result indicated by clot formation in tube following 24-hour incubation; free coagulase converts prothrombin to thrombin which converts fibrinogen to fibrin
 
*Biochemical tests to differentiate ''S. aureus'' and ''S. intermedius''
 
*Biochemical tests to differentiate ''S. aureus'' and ''S. intermedius''
 
*PCR to differentiate species
 
*PCR to differentiate species
      
===Pathogenesis and pathogenicity===
 
===Pathogenesis and pathogenicity===
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