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==Organization of Bone==
 
==Organization of Bone==
 
*Normal progression is from woven bone to lamellar bone, even in pathology, except for [[Bones - hyperplastic and neoplastic#Craniomandibular osteopathy|canine craniomandibular osteopathy]] and [[Bones - metabolic#Hypervitaminosis D|hypervitaminosis D]], where lamellar bone is replaced by woven bone
 
*Normal progression is from woven bone to lamellar bone, even in pathology, except for [[Bones - hyperplastic and neoplastic#Craniomandibular osteopathy|canine craniomandibular osteopathy]] and [[Bones - metabolic#Hypervitaminosis D|hypervitaminosis D]], where lamellar bone is replaced by woven bone
   
*'''Woven bone''':
 
*'''Woven bone''':
 
**"Random weave" which is only a normal feature in the foetus
 
**"Random weave" which is only a normal feature in the foetus
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**Later removed by osteoclasts and replaced by lamellar bone
 
**Later removed by osteoclasts and replaced by lamellar bone
 
**In adults it is a sign of a pathological condition (e.g. fracture, inflammation, neoplasia)
 
**In adults it is a sign of a pathological condition (e.g. fracture, inflammation, neoplasia)
   
*'''Lamellar bone''':
 
*'''Lamellar bone''':
 
**Orderly layers which are much stronger than woven bone
 
**Orderly layers which are much stronger than woven bone
 
**Fine collagen fibres in concentric or parallel laminae
 
**Fine collagen fibres in concentric or parallel laminae
   
**Two main types:
 
**Two main types:
 
***'''Compact bone (cortical)'''  
 
***'''Compact bone (cortical)'''  
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****Consists of cells and interstitial substance - 30% ossein (type of collagen) and 70% minerals, especially calcium phosphate
 
****Consists of cells and interstitial substance - 30% ossein (type of collagen) and 70% minerals, especially calcium phosphate
 
****Forms the shell of long bone shafts - contain [[Haversian systems]]
 
****Forms the shell of long bone shafts - contain [[Haversian systems]]
   
***'''Cancellous bone (spongy or trabecular)'''  
 
***'''Cancellous bone (spongy or trabecular)'''  
 
****Stacks of parallel or concentrically stacked sheets arranged as rods, plates, and arches
 
****Stacks of parallel or concentrically stacked sheets arranged as rods, plates, and arches
 
****In vertebrae, flat bones and forms the hematopoeitic center of epiphyses of long bones
 
****In vertebrae, flat bones and forms the hematopoeitic center of epiphyses of long bones
 
****Contains no Haversian systems
 
****Contains no Haversian systems
   
*'''Laminar bone'''
 
*'''Laminar bone'''
 
**Formed on periosteal surface of diaphysis
 
**Formed on periosteal surface of diaphysis
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