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| *AKA contagious pustular dermatitis, Orf, etc | | *AKA contagious pustular dermatitis, Orf, etc |
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− | ===General information=== | + | ====General information==== |
| *CE is an acute debilitating but rarely fatal skin disease of sheep, goats and incidentally of ruminants and humans. | | *CE is an acute debilitating but rarely fatal skin disease of sheep, goats and incidentally of ruminants and humans. |
| *The disease is generally mild. | | *The disease is generally mild. |
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| *PPV's generally exhibit a highly restricted host range but in all cases can also infect man. | | *PPV's generally exhibit a highly restricted host range but in all cases can also infect man. |
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− | ===Aetiological agent=== | + | ====Aetiological agent==== |
| *The virus is a large, enveloped, highly epitheliotropic, DNA virus which is ovoid in shape and measures 220‑300 x 140‑170 nm. *There are over 100 polypeptides in the virion. | | *The virus is a large, enveloped, highly epitheliotropic, DNA virus which is ovoid in shape and measures 220‑300 x 140‑170 nm. *There are over 100 polypeptides in the virion. |
| *The core proteins include a transcriptase and several other enzymes. | | *The core proteins include a transcriptase and several other enzymes. |
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| *The virus is resistant to desiccation. | | *The virus is resistant to desiccation. |
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− | ===Pathology=== | + | ====Pathology==== |
| [[Image:f00358.jpg]] | | [[Image:f00358.jpg]] |
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− | ===Differential diagnosis=== | + | ====Differential diagnosis==== |
| * Sheep pox: A more severe disease, it is characterized by elevated papules distributed diffusely over the skin surface. Inclusion bodies are often seen, but there is no down‑growth of epidermis. There is a high mortality. | | * Sheep pox: A more severe disease, it is characterized by elevated papules distributed diffusely over the skin surface. Inclusion bodies are often seen, but there is no down‑growth of epidermis. There is a high mortality. |
| * Ulcerative dermatosis: Characterized by ulcers and crusts on the skin of the face, feet and genitalia. The lesions are not elevated because there is no epithelial hyperplasia. | | * Ulcerative dermatosis: Characterized by ulcers and crusts on the skin of the face, feet and genitalia. The lesions are not elevated because there is no epithelial hyperplasia. |