Changes

}}

}}

<br>

<br>

==Porcine Juvenile Pustular Psoriasiform Dermatitis (Pityriasis rosea)==

==Porcine Juvenile Pustular Psoriasiform Dermatitis (Pityriasis rosea)==

===General===

===General===

*Pityriasis rosea is a self‑limiting inflammatory disease of young pigs.   

*Pityriasis rosea is a self‑limiting inflammatory disease of young pigs.   

*The condition most frequently occurs in young pigs, 3‑14 weeks of age, and often more than one member of a litter is affected.

*The condition most frequently occurs in young pigs, 3‑14 weeks of age, and often more than one member of a litter is affected.

*'''Although this condition had been previously called pityriasis rosea, clinically and pathologically it is nothing like pityriasis rosea in humans!'''

*'''Although this condition had been previously called pityriasis rosea, clinically and pathologically it is nothing like pityriasis rosea in humans!'''

===Clinical Signs===   

===Clinical Signs===   

*There are usually no systemic signs.  Skin lesions may be preceded by anorexia, vomiting, & diarrhea.   

*There are usually no systemic signs.  Skin lesions may be preceded by anorexia, vomiting, & diarrhea.   

*There is no fever.

*There is no fever.

===Gross Lesions===

===Gross Lesions===

*Primary lesions are seen on the ventral abdomen or medial thighs, and appear as symmetric, sharply defined, red raised plaques up to 6 mm in diameter.   

*Primary lesions are seen on the ventral abdomen or medial thighs, and appear as symmetric, sharply defined, red raised plaques up to 6 mm in diameter.   

**The term pseudo-ringworm has been used to describe this condition.   

**The term pseudo-ringworm has been used to describe this condition.   

*Lesions are nonirritant and usually resolve spontaneously in 2 ‑ 10 weeks.

*Lesions are nonirritant and usually resolve spontaneously in 2 ‑ 10 weeks.

===Microscopic Lesions===

===Microscopic Lesions===

*Skin biopsy reveals superficial perivascular dermatitis with psoriasiform epidermal hyperplasia.   

*Skin biopsy reveals superficial perivascular dermatitis with psoriasiform epidermal hyperplasia.   

*Intra-epidermal pustules containing eosinophils and neutrophils are prominent in early lesions.   

*Intra-epidermal pustules containing eosinophils and neutrophils are prominent in early lesions.   

*Parakeratotic hyperkeratosis is usually prominent.

*Parakeratotic hyperkeratosis is usually prominent.

===Differential Diagnosis===

===Differential Diagnosis===

#Dermatophytosis ‑ (etio: Tr. mentagrophytes, M. canis, Tr. verrucosum var. discoides, M. nanum, Tr. rubrum) Ruled‑out due to lack of mycotic organisms.

#Dermatophytosis ‑ (etio: Tr. mentagrophytes, M. canis, Tr. verrucosum var. discoides, M. nanum, Tr. rubrum) Ruled‑out due to lack of mycotic organisms.

#Dermatosis vegetans ‑ Systemic, erythematous maculopapular dermatitis caused by the inheritance of a autosomal recessive, semilethal factor.  Skin, coronary band and hoof lesions, giant cell pneumonia, fatal.

#Dermatosis vegetans ‑ Systemic, erythematous maculopapular dermatitis caused by the inheritance of a autosomal recessive, semilethal factor.  Skin, coronary band and hoof lesions, giant cell pneumonia, fatal.

#Swinepox ‑ Ballooning degeneration and intracytoplasmic inclusion bodies.

#Swinepox ‑ Ballooning degeneration and intracytoplasmic inclusion bodies.

===Postgraduate===

===Postgraduate===

Kate

Kate

::''IL-3 is involved... Vet Path (2007)  34: 45-43''

::''IL-3 is involved... Vet Path (2007)  34: 45-43''