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*Immediate reaction
 
*Immediate reaction
 
*Includes:
 
*Includes:
**[[Skin - immunologic#Atopy|Atopic dermatitis]]
+
**[[Skin Immunologic - Pathology#Atopy|Atopic dermatitis]]
 
**[[Skin Glossary - Pathology|Urticaria]]
 
**[[Skin Glossary - Pathology|Urticaria]]
 
**Angioedema
 
**Angioedema
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*In skin - circulating antibody to proteins of desmosomes in intercellular areas along basement membranes at epidermal-dermal junction
 
*In skin - circulating antibody to proteins of desmosomes in intercellular areas along basement membranes at epidermal-dermal junction
 
*Includes:
 
*Includes:
**[[Skin - immunologic#Pemphigus|Pemphigus]]
+
**[[Skin Immunologic - Pathology#Pemphigus|Pemphigus]]
**[[Skin - immunologic#Bullous pemphigoid|Bullous pemphigoid]]
+
**[[Skin Immunologic - Pathology#Bullous pemphigoid|Bullous pemphigoid]]
    
===Type III reactions===
 
===Type III reactions===
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*Immune complex vasculitis -> [[General Pathology - Haemorrhage#Purpura haemorrhagica|purpura haemorrhagica]]
 
*Immune complex vasculitis -> [[General Pathology - Haemorrhage#Purpura haemorrhagica|purpura haemorrhagica]]
 
*Includes:
 
*Includes:
**[[Skin - immunologic#Lupus erythematosus|Systemic lupus erythematosus]]
+
**[[Skin Immunologic - Pathology#Lupus erythematosus|Systemic lupus erythematosus]]
**[[Skin - immunologic#Dermatomyositis|Canine dermatomyositis]]
+
**[[Skin Immunologic - Pathology#Dermatomyositis|Canine dermatomyositis]]
    
===Type IV reactions===
 
===Type IV reactions===
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===Atopy===
 
===Atopy===
   −
*Involves [[Skin - immunologic#Type I reactions|Type I reaction]]
+
*Involves [[Skin Immunologic - Pathology#Type I reactions|Type I reaction]]
 
*Mainly causes pruritus
 
*Mainly causes pruritus
 
*Dogs - face rubbing and foot licking; secondary [[Bacterial skin infections - Pathology#Pyoderma|pyoderma]] or seborrhea
 
*Dogs - face rubbing and foot licking; secondary [[Bacterial skin infections - Pathology#Pyoderma|pyoderma]] or seborrhea
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===Flea bite hypersensitivity===
 
===Flea bite hypersensitivity===
   −
*Usually involves [[Skin - immunologic#Type I reactions|Type I reaction]] and [[Skin - immunologic#Type IV reactions|Type IV reaction]] and cutaneous basophil hypersensitivity
+
*Usually involves [[Skin Immunologic - Pathology#Type I reactions|Type I reaction]] and [[Skin Immunologic - Pathology#Type IV reactions|Type IV reaction]] and cutaneous basophil hypersensitivity
 
*Mainly dorsolumbosacral area involved, abdomen, caudomedial thighs, flanks, neck of cats
 
*Mainly dorsolumbosacral area involved, abdomen, caudomedial thighs, flanks, neck of cats
 
*Secondary trauma is self-inflicted
 
*Secondary trauma is self-inflicted
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===Culicoides hypersensitivity===
 
===Culicoides hypersensitivity===
   −
*Usually involves [[Skin - immunologic#Type I reactions|Type I reaction]] and [[Skin - immunologic#Type IV reactions|Type IV reaction]]  due to salivary antigens of ''Culicoides'' sp.
+
*Usually involves [[Skin Immunologic - Pathology#Type I reactions|Type I reaction]] and [[Skin Immunologic - Pathology#Type IV reactions|Type IV reaction]]  due to salivary antigens of ''Culicoides'' sp.
 
*May be seasonally recurring or continuous depending on climate
 
*May be seasonally recurring or continuous depending on climate
 
*Grossly:
 
*Grossly:
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===Allergic contact dermatitis===
 
===Allergic contact dermatitis===
   −
*Usually involves [[Skin - immunologic#Type IV reactions|Type IV reaction]]
+
*Usually involves [[Skin Immunologic - Pathology#Type IV reactions|Type IV reaction]]
 
*Pruritic lesions with self-inflicted trauma
 
*Pruritic lesions with self-inflicted trauma
 
*At areas in contact with allergen
 
*At areas in contact with allergen

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