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==Metabolic Disease==
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* Forebrain function may be altered by a variety of metabolic disturbances, including:
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** [[Liver - Anatomy & Physiology|Liver]] disease
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** Renal disease
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** [[Pancreas - Anatomy & Physiology|Pancreatic]] disease
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** Hypo/hyper-glycaemia
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** Electrolyte abnormalities
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** Acid-base abnormalities.
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* Generally, the nervous system signs of these diseases are diffuse and often symmetrical in the rostrotentorial area.
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* Strucural disease of the brain may result
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** This may cause focal neurological deficits.
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===Diagnosis===
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* Clinical signs are used in conjunction with biochemical studies of the affected organs or systems.

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