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***Continually turned over
 
***Continually turned over
 
***The most vulnerable component of cartilage
 
***The most vulnerable component of cartilage
***Decresed proteoglycan -> loss of lubrication -> collagen disruption -> frays, clefts, fibrillation, ulcers, exposure of bone, [[Musculoskeletal terminology|eburnation, +/- osteophytes and joint mice]]
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***Decresed proteoglycan -> loss of lubrication -> collagen disruption -> frays, clefts, fibrillation, ulcers, exposure of bone, [[Musculoskeletal Terminology - Pathology|eburnation, +/- osteophytes and joint mice]]
 
**Hyaluronic acid  
 
**Hyaluronic acid  
 
**75% Water
 
**75% Water