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===Aetiology===
 
===Aetiology===
 
*Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional
 
*Hypoplasia of [[Pancreas - Anatomy & Physiology#Endocrine|panceatic islets]] where [[Pancreas - Anatomy & Physiology|exocrine]] cells are functional
*Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreas - degenerative#Acute pancreatic necrosis|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreas Inflammatory - Pathology#Chronic interstitial pancreatitis|chronic interstitial pancreatitis]]
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*Degeneration of the [[Pancreas - Anatomy & Physiology#Endocrine|islet]] cells occurs in [[Pancreas Degenerative - Pathology#Acute pancreatic necrosis|acute pancreatic necrosis]] along with acinar tissue necrosis, atrophy occurs during [[Pancreas Inflammatory - Pathology#Chronic interstitial pancreatitis|chronic interstitial pancreatitis]]
 
*Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss
 
*Extensive neoplastic destruction may also contribute to [[Pancreas - Anatomy & Physiology#Endocrine|islet]] loss
 
*Causes [[DM|Diabetes mellitus]] (DM)
 
*Causes [[DM|Diabetes mellitus]] (DM)
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**'''Sclerosis''' of the islets is sometimes observed in dogs with [[DM|DM]] without pancreatic necrosis but also in dogs without DM
 
**'''Sclerosis''' of the islets is sometimes observed in dogs with [[DM|DM]] without pancreatic necrosis but also in dogs without DM
 
<br>
 
<br>
'''For degeneration of exocrine tissue''' see [[Pancreas - degenerative|'degenerative disease of exocrine pancreas in Alimentary section']]
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'''For degeneration of exocrine tissue''' see [[Pancreas Degenerative - Pathology|'degenerative disease of exocrine pancreas in Alimentary section']]
 
==Neoplasia==
 
==Neoplasia==
 
[[Image:Islet cell tumour.jpg|right|thumb|100px|<small><center>Islet cell tumour (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]
 
[[Image:Islet cell tumour.jpg|right|thumb|100px|<small><center>Islet cell tumour (Image sourced from Bristol Biomed Image Archive with permission)</center></small>]]

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