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| | + | ==Congenital melanosis== |
| | + | *in calves and lambs |
| | + | *black discoloration of small irregular portions of the [[Liver - Anatomy & Physiology|liver]] |
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| | + | ==Haemosiderin== |
| | + | *in chronic passive congestion and surrounding areas where there has been prior necrosis and haemorrhage |
| | + | *found within the Kuppfer cells |
| | + | *use Perls' stain |
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| | + | ==Lipofuscin== |
| | + | *an insoluble golden brown pigment which occurs within hepatocytes |
| | + | *use Schmorl's stain - dark blue |
| | + | *increases with age - called the ''''senility' pigment''' |
| | + | *it is commonly seen in hepatocytes near to the centrilobular vein in older cats |
| | + | *no clinical significance |
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| | + | ==Bile== |
| | + | *especially prominent in obstructive jaundice |
| | + | *discolours the tissues green |
| | + | *intrahepatic bile canaliculi are distended with a greenish pigment - called '''bile plugs''' |
| | + | *larger foci are seen in long standing cases when the hepatocytes rupture: the discharged bile is then surrounded by macrophages and perhaps giant cells - called '''bile lakes''' |
| | + | *use Fouchet stain - green |