When the embryo is in it's blastula stage it has two cell layers; the epiblast and hypoblast. The epiblast is columnar whilst the hypoblast is cubiodal - each is a single cell thick. '''The epiblast gives rise to all three cell layers; the hypoblast makes no contribution'''. The endoderm and mesoderm develop by proliferation and migration of cells of the epiblast. What remains of the epiblast forms the ectoderm.
+
*When the embryo is in it's blastula stage it has two cell layers; the epiblast and hypoblast.
+
**The epiblast is columnar whilst the hypoblast is cubiodal - each is a single cell thick.
+
*'''The epiblast gives rise to all three cell layers; the hypoblast makes no contribution'''.
+
*The endoderm and mesoderm develop by proliferation and migration of cells of the epiblast.
+
**What remains of the epiblast forms the ectoderm.