Line 73: |
Line 73: |
| **They then migrate laterally and anteriorly. | | **They then migrate laterally and anteriorly. |
| *As the streak extends further, it enters the intermediate and paraxial mesoderm territories, which ingress in a similar fashion. | | *As the streak extends further, it enters the intermediate and paraxial mesoderm territories, which ingress in a similar fashion. |
− | *Cells of the LPM are most lateral, then intermediate followed by paraxial mesoderm and axial mesoderm. | + | *Cells of the LPM are most lateral, then intermediate followed by paraxial mesoderm. |
− | *As ingression continues, the hypoblast is pushed laterally as the endoderm spreads. | + | *As ingression continues and the endoderm continues to interchalate, the hypoblast is pushed laterally. |
| + | |
| + | ==Gastrulation at the Node== |
| + | |
| + | *The primitive streak stops elongating at about 75% of the way along the length of the posterior - anterior axis. |
| + | **Cells condense at this anterior point of the primitive streak and continue to proliferate. |
| + | **They then ingress and replace the anterior hypoblast and form foregut endoderm. |
| + | **Cells then migrate anteriorly, leaving the node. These cells will form all of the head mesoderm. |
| + | ***The node then regresses posteriorly, destroying the primitive streak and forming the '''notochord''' (axial mesoderm). |
| + | ***The notochord begins at the level of the midbrain. |
| + | ****Anterior cells are developing before posterior cells have even undergone gastrulation. |
| + | |
| + | ==Gastrulation at the Tail Bud== |
| + | |
| + | *Cells at the posterior of the primitive streak are allocated to form the tail bud. When the primitive streak elongates, these cells don't follow, but migrate posteriorly and form a condensed ball of cells called the tail bud. |
| + | *The tail bud exists to form cells of the hindlimb. |
| + | *Tail notochord and somites form through regression of the tail bud. |
| + | **'''No endoderm exists in the tail bud.''' |
| + | *Without the tail bud, the notochord would run out of cells before the hindlimb could be made. |
| + | *In animals that have tails, cells at an additional site undergo gastrulation. |