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==Introduction==
 
==Introduction==
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Production of IgM or IgG to cell surface antigens or extracellular matrix proteins.
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Production of [[Immunoglobulin M - WikiBlood|IgM]] or [[Immunoglobulin G - WikiBlood|IgG] to cell surface antigens or extracellular matrix proteins.
    
==Mechanism==
 
==Mechanism==
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1. Antibody dependent cell cytotoxicity (ADCC)
 
1. Antibody dependent cell cytotoxicity (ADCC)
* Pemphigus vulgaris
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* [[Autoimmune Diseases - WikiBlood|Pemphigus vulgaris]]
* Bullous pemphigoid
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* [[Autoimmune Diseases - WikiBlood|Bullous pemphigoid]]
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2. Complement mediated lysis
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2. [[Complement - WikiBlood|Complement]] mediated lysis
* Self RBC antigen:
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* Self [[Erythrocytes - WikiBlood|RBC]] antigen:
** Immune mediated haemolytic anaemia
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** [[Autoimmune Diseases - WikiBlood|Immune mediated haemolytic anaemia]]
* Foreign RBC:
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* Foreign [[Erythrocytes - WikiBlood|RBC]]:
 
** Blood transfusion reaction
 
** Blood transfusion reaction
 
** Haemolytic disease of new born (Rhesus disease in humans and neonatal isoerythrolysis in foals and kittens)
 
** Haemolytic disease of new born (Rhesus disease in humans and neonatal isoerythrolysis in foals and kittens)
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