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Muscle Development - Anatomy & Physiology (view source)
Revision as of 08:42, 31 August 2008
, 08:42, 31 August 2008no edit summary
==Muscle Development==
==Muscle Cell Differentiation==
#'''Prescursor''' cells migrate from the dermomyotome.
#'''Prescursor''' cells migrate from the dermomyotome.
#The '''myofibre''' is produced.
#The '''myofibre''' is produced.
#*Contractile proteins are present.
#*Contractile proteins are present.
==Limb Muscle Development==
*Skeletal muscle of the limbs originates from those somites closest to the limbs.
#Signalling factors from the limbs cause cells to migrate from the somite.
#*Singalling factors cause the hypaxial lamina to break down.
#*This allows cells to migrate.
#*''Few cells migrate; but they rapidly prolifate during migration to increase cell numbers.''
#Muscle precursors migrate into the limb bud (proliferating).
#*At the proximal region of the limb, two populations of cells exists.
#*These are the dorsal and ventral masses.
#Cells continue migration within these populations.
#Once cells have reached their destinations, they differentiate.