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New page: {{toplink |backcolour =CDE472 |linkpage =Musculoskeletal System - Pathology |linktext =Musculoskeletal System |maplink = Musculoskeletal System (Content Map) - Pathology |pagetype =Patholo...
{{toplink
|backcolour =CDE472
|linkpage =Musculoskeletal System - Pathology
|linktext =Musculoskeletal System
|maplink = Musculoskeletal System (Content Map) - Pathology
|pagetype =Pathology
|sublink1=Muscles Degenerative - Pathology
|subtext1=MUSCLES DEGENERATIVE
}}
<br>
Also known as '''Stiff lamb disease''', characterised by myodegeneration. Disease is stress induced so the breakdown of muscle relies on increased muscle activity. Muscle degenerates due to a failure to control the free radicals produced by its metabolism upon contraction. Free radicals damage cellular membranes and proteins.
Muscle damage allows the release of:
*Potassium: can lead to heart failure.
*Myoglobin: can lead to renal failure.
*Creatine Kinase: useful to measure muscle damage.
Grossly the damaged muscle will contain white streaks.
The damage caused by Zenker degeneration is reversible if the sarcolemma remains intact.
|backcolour =CDE472
|linkpage =Musculoskeletal System - Pathology
|linktext =Musculoskeletal System
|maplink = Musculoskeletal System (Content Map) - Pathology
|pagetype =Pathology
|sublink1=Muscles Degenerative - Pathology
|subtext1=MUSCLES DEGENERATIVE
}}
<br>
Also known as '''Stiff lamb disease''', characterised by myodegeneration. Disease is stress induced so the breakdown of muscle relies on increased muscle activity. Muscle degenerates due to a failure to control the free radicals produced by its metabolism upon contraction. Free radicals damage cellular membranes and proteins.
Muscle damage allows the release of:
*Potassium: can lead to heart failure.
*Myoglobin: can lead to renal failure.
*Creatine Kinase: useful to measure muscle damage.
Grossly the damaged muscle will contain white streaks.
The damage caused by Zenker degeneration is reversible if the sarcolemma remains intact.