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Nephron Microscopic Anatomy (view source)
Revision as of 13:08, 3 September 2008
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==Glomerulus==
[[Image:normcorpusclekidapx.jpg|right|thumb|200px|<small><center>Histology section of a normal renal corpuscle (© RVC 2008)</center></small>]]
[[Image:normcorpusclekidap2.jpg|right|thumb|200px|<small><center>Histology section of a normal renal corpuscle (© RVC 2008)</center></small>]]
[[Image:normcorpusclebowmankidap.jpg|right|thumb|200px|<small><center>Histology section of a normal renal corpuscle showing the layers of the bowmans capsule (© RVC 2008)</center></small>]]
* Made up of many parallel capillaries
* These capillaries do not connect to venules as with other capillaries
* Blood flows into these capillaries through a wide afferent arteriole and leaves through a narrower efferent arteriole
* The flow from the efferant arteriole enters the [[Peritubular Capillaries - Anatomy & Physiology|peritubular capillaries]] surrounding the [[Proximal Tubule - Anatomy & Physiology| Proximal Tubule]]
* This change in diameter maintains a high filtration pressure which is essential for filtration
* Also the blood entering the afferent arteriole is at very high pressure already as it from the renal artery
* The pressure actually forces molecules through the '''glomerular filtration barrier''' which is responsible for selectively filtering the blood forming the glomerular filtrate.
* As well as the the cells in the blood vessels the other component of the glomerulus are the mesangial cells:
** These give support to the glomerulus
** Maintain glomerular basal lamina
==Bowmans Capsule==
* Surrounds the capillaries of the glomerulus
* Has two layers
** Inner visceral layer - Podocytes
** Outer parietal layer
* It is here where the filtrate is collected before entering the proximal tubule