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| + | ==Glomerulus== |
| + | [[Image:normcorpusclekidapx.jpg|right|thumb|200px|<small><center>Histology section of a normal renal corpuscle (© RVC 2008)</center></small>]] |
| + | [[Image:normcorpusclekidap2.jpg|right|thumb|200px|<small><center>Histology section of a normal renal corpuscle (© RVC 2008)</center></small>]] |
| + | [[Image:normcorpusclebowmankidap.jpg|right|thumb|200px|<small><center>Histology section of a normal renal corpuscle showing the layers of the bowmans capsule (© RVC 2008)</center></small>]] |
| + | * Made up of many parallel capillaries |
| + | * These capillaries do not connect to venules as with other capillaries |
| + | * Blood flows into these capillaries through a wide afferent arteriole and leaves through a narrower efferent arteriole |
| + | * The flow from the efferant arteriole enters the [[Peritubular Capillaries - Anatomy & Physiology|peritubular capillaries]] surrounding the [[Proximal Tubule - Anatomy & Physiology| Proximal Tubule]] |
| + | * This change in diameter maintains a high filtration pressure which is essential for filtration |
| + | * Also the blood entering the afferent arteriole is at very high pressure already as it from the renal artery |
| + | * The pressure actually forces molecules through the '''glomerular filtration barrier''' which is responsible for selectively filtering the blood forming the glomerular filtrate. |
| + | * As well as the the cells in the blood vessels the other component of the glomerulus are the mesangial cells: |
| + | ** These give support to the glomerulus |
| + | ** Maintain glomerular basal lamina |
| + | |
| + | ==Bowmans Capsule== |
| + | |
| + | * Surrounds the capillaries of the glomerulus |
| + | * Has two layers |
| + | ** Inner visceral layer - Podocytes |
| + | ** Outer parietal layer |
| + | * It is here where the filtrate is collected before entering the proximal tubule |