The endocrine function of the kidneys comprises the production and release of two hormones - [[Erythropoiesis - WikiBlood#Regulation|Erythropoietin]] and [[Juxtaglomerular Cells of The Distal Tubule - Renal Physiology #Renin| Renin]] both from the [[Juxtaglomerular Cells of The Distal Tubule - Renal Physiology |juxtaglomerular complexes]]. It is also responsible for the regulation of the [[Endocrine System - Calcium Homeostasis - Anatomy & Physiology #Active Vitamin D Synthesis |activation of vitamin D]]