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| + | Puberty is the process of aquiring reproductive capability. The onset depends on the ability of specific hypothalamic neurons to produce GnRH in sufficient quantities to both promote and support gametogenesis. |
| + | * In the female, hypothalamic GnRH neurons must develop the ability to respond to positive oestradiol feedback in order to produce sufficient GnRH to cause ovulation. |
| + | * Develepment of hypothalamic neurons is influenced by: |
| + | ** Development of a threshold body size. |
| + | ** Exposure to environmental and social cues. |
| + | ** Genetics |