Line 66: |
Line 66: |
| <br> | | <br> |
| <br> | | <br> |
− | ==<font color="purple">Immunoglobulins Classes</font>== | + | ==<font color="purple">Classes of Immunoglobulin</font>== |
| {| border="3" cellpadding="8" | | {| border="3" cellpadding="8" |
| !width="400"|'''Question''' | | !width="400"|'''Question''' |
Line 72: |
Line 72: |
| !width="150"|'''Article''' | | !width="150"|'''Article''' |
| |- | | |- |
− | |<big>'''What are immunoglobulins also known as?''' | + | |<big>'''How do the five classes of immunoglobulins vary from each other?''' |
| ||<font color="white"> <big> | | ||<font color="white"> <big> |
− | *'''''Antibodies''''' | + | *'''''They each have a different composition to their heavy chains''''' |
− | ||[[Immunoglobulins - WikiBlood#Introduction|<span title="Answer article">Link to Answer Article</span>]] | + | ||[[Immunoglobulins - WikiBlood#Classes|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''IgA is specially adapted for function at which type of surface?''' |
| + | ||<font color="white"> <big> |
| + | *'''''Mucosal surfaces''''' |
| + | ||[[Immunoglobulin A - WikiBlood|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''True or False: IgA is a monomer''' |
| + | ||<font color="white"> <big> |
| + | *'''''False''''' |
| + | *'''''IgA is a dimer''''' |
| + | ||[[Immunoglobulin A - WikiBlood#Structure|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''What are the functions of IgA?''' |
| + | ||<font color="white"> <big> |
| + | *'''''Prevents agents from adhering to the epithelial surfaces as it binds to foreign antigen''''' |
| + | *'''''Resists proteolytic digestion so can function in the gut''''' |
| + | *'''''Does not activate the complement system so helps to preserve mucosal integrity''''' |
| + | ||[[Immunoglobulin A - WikiBlood#Function|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''In which species has IgD been identified?''' |
| + | ||<font color="white"> <big> |
| + | *'''''Ruminants''''' |
| + | *'''''Pigs''''' |
| + | *'''''Dogs''''' |
| + | *'''''Rodents''''' |
| + | ||[[Immunoglobulin D - WikiBlood#Function|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''What is the main function of IgD?''' |
| + | ||<font color="white"> <big> |
| + | *'''''Helps B cell development''''' |
| + | ||[[Immunoglobulin D - WikiBlood#Function|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''True or False: IgE is not a soluble antibody?''' |
| + | ||<font color="white"> <big> |
| + | *'''''True''''' |
| + | ||[[Immunoglobulin E - WikiBlood|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''What are the functions of IgE?''' |
| + | ||<font color="white"> <big> |
| + | *'''''Triggers acute inflammation by causing degranulation''''' |
| + | *'''''Involved in type I hypersensitivity reactions''''' |
| + | *'''''Involved in producing immunity to parasitic worms and nematode parasites''''' |
| + | ||[[Immunoglobulin E - WikiBlood#Function|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''True or False: IgG is the smallest antibody and can easily leave the plasma and enter tissue?''' |
| + | ||<font color="white"> <big> |
| + | *'''''True''''' |
| + | ||[[Immunoglobulin G - WikiBlood|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''Where is IgG produced?''' |
| + | ||<font color="white"> <big> |
| + | *'''''Bone marrow''''' |
| + | *'''''Spleen''''' |
| + | *'''''Lymph nodes''''' |
| + | ||[[Immunoglobulin G - WikiBlood#Production|<span title="Answer article">Link to Answer Article</span>]] |
| + | |- |
| + | |<big>'''What is the function of IgG?''' |
| + | ||<font color="white"> <big> |
| + | *'''''Activates the classical pathway of the complement cascade''''' |
| + | *'''''Can act as targets for macrophages, eosinophils and neutrophils''''' |
| + | *'''''Causes agglutination and opsonisation of bacteria''''' |
| + | ||[[Immunoglobulin G - WikiBlood#Function|<span title="Answer article">Link to Answer Article</span>]] |
| |} | | |} |
| + | |
| + | '''START HERE TOMORROW WITH IG M''' |
| + | |
| <br> | | <br> |
| <br> | | <br> |
| + | |
| ==<font color="purple">Immunoglobulins Variation</font>== | | ==<font color="purple">Immunoglobulins Variation</font>== |
| {| border="3" cellpadding="8" | | {| border="3" cellpadding="8" |