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Glomerular Apparatus and Filtration - Anatomy & Physiology (view source)
Revision as of 11:22, 5 September 2008
, 11:22, 5 September 2008→Glomerular Filtration
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==Glomerular Filtration==
==Glomerular Filtration==
The role of the renal corpuscle is to selectively filter the blood by allowing small molecules through but preventing plasma proteins from leaving the blood. This filtration occurs extracellulary and is done by what is know as the '''glomerular filtration barrier'''. This structure is made up of three layers:
The role of the [[Microscopic Anatomy of the Nephron - Anatomy & Physiology#The Renal Corpuscle|renal corpuscle]] is to selectively filter the blood by allowing small molecules through but preventing plasma proteins from leaving the blood. This filtration occurs extracellulary and is done by what is know as the '''glomerular filtration barrier'''. This structure is made up of three layers:
* Fenestrated capillary endothelium
* Fenestrated capillary endothelium
* Glomerular basement membrane
* Glomerular basement membrane
* There are small gaps called fenestrae in the cytoplasm of the capillary endothelium.
* There are small gaps called fenestrae in the cytoplasm of the capillary endothelium.
* They account for approxamately 10% of the surface area of the cells
* They account for approximately 10% of the surface area of the cells
* They allow water and non-cellular components of the blood to pass through
* They allow water and non-cellular components of the blood to pass through
* They act mainly as a barrier to the cells of the blood
* They act mainly as a barrier to the cells of the blood