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Reabsorption and Secretion Along the Distal Tubule and Collecting Duct - Anatomy & Physiology (view source)
Revision as of 11:58, 5 September 2008
, 11:58, 5 September 2008→Juxtaglomerular Apparatus
** The [[Juxtaglomerular Cells of The Distal Tubule - Renal Physiology | Juxtaglomerular Cells]] are smooth muscle cells which adjoin the macula densa in the capillary wall.
** The [[Juxtaglomerular Cells of The Distal Tubule - Renal Physiology | Juxtaglomerular Cells]] are smooth muscle cells which adjoin the macula densa in the capillary wall.
** The Extraglomerular Mesangium has an unclear function
** The Extraglomerular Mesangium has an unclear function
====Juxtaglomerular Cells====
=====Function=====
* Smooth muscle cells
* Synthesise [[Useful definitions - Renal Anatomy & Physiology| renin]]
* From the [http://en.wikipedia.org/wiki/Zymogen zymogen] prerenin
* Described as intra-renal baroreceptors
** Respond to stretch
* The secretion of renin from these cells depends on the stretch
** '''If stretch decreases - blood pressure has decreased - renin secretion increases'''
* Also respond to the sympathetic nervous system
** Increases renin output
=====Renin=====
* Renin affects blood pressure indirectly
* Part of the first stage of the [[Renin-Angiotensin-Aldosterone System (RAAS) - Anatomy & Physiology| renin-angiotensin-aldosterone-system]]
** Its effects are through its activation of this system
===Developmental===
===Developmental===