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| [[Image:Passive Immunisation.jpg|thumb|right|150px|Passive Immunisation - Copyright nabrown RVC]] | | [[Image:Passive Immunisation.jpg|thumb|right|150px|Passive Immunisation - Copyright nabrown RVC]] |
| '''Passive immunisation''' | | '''Passive immunisation''' |
− | ''Passive immunisation establishes temporary protection by the administration of preformed antibody from another individual of the same or of a different species. The aquired antibodies are used in combination with antigen and catabolised by the body meaning protection is gradually lost.''
| + | |
| + | *Advantages: |
| + | **Immediate protection |
| + | |
| + | *Disadvantages: |
| + | **Short duration of action |
| + | ***Temporary protection by the administration of preformed antibody from another individual of the same or of a different species |
| + | ***The aquired antibodies are used in combination with antigen and catabolised by the body meaning protection is gradually lost |
| + | **Injection of antiserum may cause an allergic response |
| + | **Antiserum contains many antibodies not just the specific antobodies needed |
| + | |
| *Administer antibodies | | *Administer antibodies |
| **Maternally-derived antibodies in colostrum | | **Maternally-derived antibodies in colostrum |
| **Antiserum (artificial) | | **Antiserum (artificial) |
− | | + | ***The antigen (and often an adjuvant) is injected into the host animal |
− | *Immediate protection | + | ***The immune system of that animal synthesised antibodies |
− | | + | ***Repeated injections at intervals increases the total antibody production |
− | *Short duration of action | + | ***The immunised animal is bled and the serum collected which contains the newly made antibodies. The serum is called '''antiserum'''. |
| + | ***The serum can then be injected into a different animal to confer passive immunisation |
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| *Example of when passive immunisation is used: | | *Example of when passive immunisation is used: |