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Major Histocompatability Complexes (view source)
Revision as of 12:30, 9 September 2008
, 12:30, 9 September 2008→MHC I
*** Not membrane associated
*** Not membrane associated
**** But binds to the α3-domain of the heavy chain
**** But binds to the α3-domain of the heavy chain
[[Image:MHC I Structure.jpg|thumb|right|150px| Structure of MHC I molecule - Copyright Prof Dirk Werling DrMedVet PhD MRCVS]]
* The MHC class I domains are structurally and genetically related to immunoglobulin and TcR domains
* The MHC class I domains are structurally and genetically related to immunoglobulin and TcR domains
** The outer domains (α1 and α2) are like the variable domains
** The outer domains (α1 and α2) are like the variable domains