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Follicles - Anatomy & Physiology (view source)
Revision as of 13:39, 9 September 2008
, 13:39, 9 September 2008→'''Secondary Follicles'''
* Connective tissue cells surrounding the granulosa cells differentiate to form the layers of theca cells which produce androgens.
* Connective tissue cells surrounding the granulosa cells differentiate to form the layers of theca cells which produce androgens.
* Theca cells produce Androstienedione which is converted to [[Endocrine_System_-_Ovaries_-_Anatomy_%26_Physiology|17β-Oestrodiol ]](E2) by the Granulosa cell enzyme Aromatase.
* Theca cells produce Androstienedione which is converted to [[Endocrine_System_-_Ovaries_-_Anatomy_%26_Physiology|17β-Oestrodiol ]](E2) by the Granulosa cell enzyme Aromatase.
* Granulosa cells secrete [[Endocrine_System_-_Ovaries_-_Anatomy_%26_Physiology|17β-Oestrodiol ]],[[Endocrine_System_-_Ovaries_-_Anatomy_%26_Physiology|Inhibin]] and small amounts of progesterone.
*Granulosa cells become responsive to Follicle Stimulating Hormone (FSH) and start producing [[Endocrine_System_-_Ovaries_-_Anatomy_%26_Physiology|17β-Oestrodiol]] and small amounts of Inhibin and Progesterone.
* Despite the presence of the zona pellucida, the inner granulosa cells are able to communicate with the oocyte through gap junctions.
* Despite the presence of the zona pellucida, the inner granulosa cells are able to communicate with the oocyte through gap junctions.
* Following formation of the theca cells, the primary oocyte reaches full size.
* Following formation of the theca cells, the primary oocyte reaches full size.