* Progesterone and its synthetic analogues are used extensively in most domestic species to synchronize oestrus.
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* Exogenous progestogens act in the same way as the corpus luteum, resulting in a negative feedback effect on the anterior pituitary gland.
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* This in turn results in supression of gonadotrophin release, so cyclic activity ceases.
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* When the progestogen is withdrawn, the negative feedback block on the anterior pituitary gland is removed. This initiates a retun to cyclic activity.
= Manipulation of the Oestrous Cycle in Various Species =
= Manipulation of the Oestrous Cycle in Various Species =