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Maternal Recognition of Pregnancy - Anatomy & Physiology (view source)
Revision as of 21:56, 13 September 2008
, 21:56, 13 September 2008→Sow
* The pig conceptus produces oestradiol as the signal for maternal recognition of pregnancy.
* The pig conceptus produces oestradiol as the signal for maternal recognition of pregnancy.
* Also, PGF2α is produced in significant quantities, but is rerouted into the uterine lumen.
* Also, PGF2α is produced in significant quantities, but is re-routed into the uterine lumen.
* Oestradiol is produced 11-12 days after ovulation. This does not inhibit secretion of PGF2α , but causes it to be secreted in a different direction than in a cycling sow.
* Oestradiol is produced 11-12 days after ovulation. This does not inhibit secretion of PGF2α , but causes it to be secreted in a different direction than in a cycling sow.
* It is thought that prolactin production in the uterine endometrium increases under the influence of oestradiol. This acts to change the ionic flux for calcium, promoting exocrine secretion of PGF2α.
* It is secreted away from submucosal capillaries, towards the uterine lumen.
* It is secreted away from submucosal capillaries, towards the uterine lumen.
* Luminal PGF2α has little access to the circulation, and thus cannot cause luteolysis.
* Luminal PGF2α has little access to the circulation, and thus cannot cause luteolysis.
* Oestadiol also inactivates PGE2-9 oxoreductase,preventing the conversion of PGE2 to PGF2α.
* Production of oestradiol not only prevents luteolysis, but serves to stimulate contractions of the uterine myometrium. This ensures distribution of the conceptuses with proper spacing along the uterine horns.
* Production of oestradiol not only prevents luteolysis, but serves to stimulate contractions of the uterine myometrium. This ensures distribution of the conceptuses with proper spacing along the uterine horns.
=== Conceptus ===
=== Conceptus ===