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'''Regulation of Synthesis and Secretion'''
 
'''Regulation of Synthesis and Secretion'''
 
This is regulated by the hypothalamus-pituitary adrenal axis as follows:
 
This is regulated by the hypothalamus-pituitary adrenal axis as follows:
 +
[[Image:ACTH axis.jpg|right|thumb|205px|<small><center>'''Schematic Diagram of the Hypothalamic Pituitary Adrenal Axis</center></small>]]
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* An environmental or internal stimuli (such as stress or light regulating the circadian rhythm) causes the hypothalamus to release ACTH-releasing hormone ('''ACTH-RH''').
 
* An environmental or internal stimuli (such as stress or light regulating the circadian rhythm) causes the hypothalamus to release ACTH-releasing hormone ('''ACTH-RH''').
 
* ACTH-RH flows to the pituitary gland stimulating the production of adrenocorticotrophic hormone ('''ACTH''').
 
* ACTH-RH flows to the pituitary gland stimulating the production of adrenocorticotrophic hormone ('''ACTH''').
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