Changes

**Similar to [[Skin Immunologic - Pathology#Pemphigus|Pemphigus vulgaris]]

**Similar to [[Skin Immunologic - Pathology#Pemphigus|Pemphigus vulgaris]]

*Microscopically:

*Microscopically:

**Bullae containing fibrin, [[Neutrophils - WikiBlood|neutrophils]] or eosinophils

**Bullae containing fibrin, [[Neutrophils - WikiBlood|neutrophils]] or [[Eosinophils - WikiBlood|eosinophils]]

**Basement membrane forms floor of bullae and roof is lined with basal cells

**Basement membrane forms floor of bullae and roof is lined with basal cells

*Bullae may rupture -> ulcers

*Bullae may rupture -> ulcers

****Acantholytic cells

****Acantholytic cells

****Subcorneal or intragranular pustules

****Subcorneal or intragranular pustules

****In third of equine or canine cases eosinophils are predominant

****In third of equine or canine cases [[Eosinophils - WikiBlood|eosinophils]] are predominant

**'''Pemphigus erythematosus'''

**'''Pemphigus erythematosus'''

***Cats and dogs

***Cats and dogs

***Mild form of P. foliaceus

***Mild form of P. foliaceus

***Usually involves only face and external ears

***Usually involves only face and external ears