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Newcastle Disease Virus (view source)
Revision as of 18:27, 13 October 2008
, 18:27, 13 October 2008New page: {{toplink |linkpage = Paramyxoviridae |linktext = PARAMYXOVIRIDAE |pagetype=Bugs }} <br> ====Hosts==== *Gallinaceous birds, pigeons, parrots, finches *Subclinical carriers: ducks, ostric...
{{toplink
|linkpage = Paramyxoviridae
|linktext = PARAMYXOVIRIDAE
|pagetype=Bugs
}}
<br>
====Hosts====
*Gallinaceous birds, pigeons, parrots, finches
*Subclinical carriers: ducks, ostriches
*Causes conjunctivitis in humans
====Pathogenesis====
*Transmission via aerosol and direct contact
*Disease ranges from subclinical [[Respiratory Viral Infections - Pathology|respiratory tract infections]] -> torticollis -> haemorrhages and death
====Diagnosis====
Two diagnostic tests currently exist:
*Animal test:
**Samples of trachea and gut of 20 birds are tested in eggs
**'''HI''' using anti-NDV serum (to differentiate '''HA''' caused by [[Orthomyxoviridae#Avian Influenza|avian influenza]]
**Virulence of isolate tested by the speed it kills chicks
*DNA test (which will soon replace the animal test):
**Sequencing the cleavage site of H gene
**The more basic amino acids the more virulent the virus
====Control====
*Newcastle Disease is '''NOTIFIABLE'''
*Vaccination of chickens and racing pigeons
*Surveillance of imported exotic birds
*Isolation of infected stock
*Infected premises to be culled and firebreak cull if spread
|linkpage = Paramyxoviridae
|linktext = PARAMYXOVIRIDAE
|pagetype=Bugs
}}
<br>
====Hosts====
*Gallinaceous birds, pigeons, parrots, finches
*Subclinical carriers: ducks, ostriches
*Causes conjunctivitis in humans
====Pathogenesis====
*Transmission via aerosol and direct contact
*Disease ranges from subclinical [[Respiratory Viral Infections - Pathology|respiratory tract infections]] -> torticollis -> haemorrhages and death
====Diagnosis====
Two diagnostic tests currently exist:
*Animal test:
**Samples of trachea and gut of 20 birds are tested in eggs
**'''HI''' using anti-NDV serum (to differentiate '''HA''' caused by [[Orthomyxoviridae#Avian Influenza|avian influenza]]
**Virulence of isolate tested by the speed it kills chicks
*DNA test (which will soon replace the animal test):
**Sequencing the cleavage site of H gene
**The more basic amino acids the more virulent the virus
====Control====
*Newcastle Disease is '''NOTIFIABLE'''
*Vaccination of chickens and racing pigeons
*Surveillance of imported exotic birds
*Isolation of infected stock
*Infected premises to be culled and firebreak cull if spread