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New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Orthomyxoviridae |subtext1=INFLUENZA |pagetype =Bugs }} <br> ===Subtypes=== *H1-15 and N1-9 have all been isolate...
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{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Orthomyxoviridae
|subtext1=INFLUENZA
|pagetype =Bugs
}}
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===Subtypes===
*H1-15 and N1-9 have all been isolated
*Highly Pathogenic Avian Influenza (HPAI), caused by H5 and H7 isolates, is also known as Fowl Plague (FP) and is notifiable
**Chinese poultry are currently the main reservoir for H5N1, not wild birds
===Pathogenesis===
*HPAI is defined by:
**Heamorrhages
**Diarrhoea
**Sometimes nervous symptoms
**Sudden death
*H5 spread by feces and infected viscera (kidney/spleen are 100X more infectious than feces)
*H7 and other viruses are carried by 6% of the wild bird population and outbreaks mirror migrating patterns
**This poses significant risk to free-range flocks
===Zoonotic potential===
*A 2003 Dutch outbreak of a pathogenic H7 virus caused widespread conjunctivitis and flu-like symptoms with recovery among poultry workers
*Rural chinese children became infected with H5N1 via aerosol transmission, which was limited to upper respiratory symptoms and did not show horizontal spread
===Control===
*Prevention by proper hygiene and preventing contact with the wild bird population
*Isolation and cull of infected premises
*Firebreak cull in the case of uncontrolled spread
*Vaccination is not currently practiced for the following reasons:
**An eradication policy prevents it
**Vaccination favors the evolution of the virus, which might increase its virulence and drift
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